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The successor to the Jarvik-3 artificial heart was modeled after the human heart and is approximately the same size as a human's fist-sized heart. It weighs about ten ounces and is designed to replace the human heart. It has two artificial ventricles, which are like the pumping chambers of the heart and which replace the left and right ventricles, which the surgeon has removed. The device is made up of Dacron polyester, aluminum, and plastic. The patient's atria, the upper chambers of the heart that take in blood from the veins, is the anchor to which the Jarvik-7 heart is attached. The power for the device comes from an outside device that is connected to the patient's chest through tubes. As a result, the artificial heart duplicates the functioning of the human heart. The right atrium receives blood from the body, then pushes it down to the right ventricle, which pumps it to the lungs through pulmonary arteries to pick up oxygen. The oxygenated blood goes through the pulmonary arteries to the left atrium and is again pushed down, this time to the left ventricle through the mitral valve. The left ventricle then pumps the blood, after the mitral valve is closed and the aortic opened, to the rest of the body through the aorta. Essentially, the Jarvik-7 consists of the two ventricles, which comprise about two-thirds of the human heart.

During the 1990's, Jarvik began developing the Jarvik 2000, a heart assist device that is placed in the patient's left ventricle, where its propeller pumps up to 1,500 gallons of blood daily. The device received FDA approval as a "bridge" between heart transplants. In 2006, researchers at Abiomed received FDA approval for their AbioCor replacement heart. Their artificial heart, made of plastic and titanium, is the size of a softball and weighs approximately three pounds. Unlike the Jarvik-7, it has an internal power source that allows it to work for up to thirty minutes. It also has power supplied by batteries that are attached to a belt. The improvements were made possible by the research inspired by Jarvik's work. Other medical advances in artificial hearts may ultimately save thousands of lives.

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